Mechanisms of telomere regulation: characterizing TRF1-mediated phase separation of nucleosomes
Telomeres are functionally conserved regions at the ends of chromosomes that confer protection. The dysregulation of telomeres has been implicated in diseases of aging and cancer, but not all underlying mechanisms of telomere regulation have been fully elucidated. Recently, liquid-liquid phase separ...
Saved in:
Main Author: | Ng, Brendan Wei-Jie |
---|---|
Other Authors: | Lars Nordenskiöld |
Format: | Final Year Project |
Language: | English |
Published: |
Nanyang Technological University
2023
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/166549 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Liquid-liquid phase separation of telomeric nucleosome array is mediated by TRF2
by: Neo, Qi Ying
Published: (2022) -
Mechanism of telomere maintenance: HP1α mediates liquid-liquid phase separation of telomeric nucleosome array
by: Putri, Dhira Anindya
Published: (2023) -
The shelterin component TRF2 mediates columnar stacking of human telomeric chromatin
by: Wong, Sook Yi, et al.
Published: (2024) -
Interaction of TRF2-Rap1 with telomeric chromatin in the context of aging and cancer
by: Woo, Jia Qi
Published: (2024) -
Properties, structure and dynamics of the telomeric nucleosome
by: Soman, Aghil
Published: (2019)