Oncofetal HMGA2 as a key regulator of telomere stability through control of DNA topology

• المؤلف الرئيسي: Dharshana, Ramani Priya
• مؤلفون آخرون: Peter Droge
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/89230; http://hdl.handle.net/10220/46217
• المؤسسة: Nanyang Technological University

Faithful replication of the whole genome is fundamental to maintain the genome integrity. During this process, the replication forks may encounter various endogenous and exogenous factors that could lead to replication fork stalling. Telomeres in particular experience numerous replication and topolo...