Novel functions of the oncofetal HMGA2 protein in genome stability
The non-histone chromatin factor HMGA2 (High Mobility Group AT-hook 2), which contains three AT-hook motifs as independent DNA binding domains, is normally expressed in ES cells and during embryonic/fetal development. In this study, I investigated its function in protecting the stalled replication f...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2014
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Online Access: | http://hdl.handle.net/10356/55737 |
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Institution: | Nanyang Technological University |
Language: | English |