Novel functions of the oncofetal HMGA2 protein in genome stability

The non-histone chromatin factor HMGA2 (High Mobility Group AT-hook 2), which contains three AT-hook motifs as independent DNA binding domains, is normally expressed in ES cells and during embryonic/fetal development. In this study, I investigated its function in protecting the stalled replication f...

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Bibliographic Details
Main Author: Yu, Haojie
Other Authors: Peter Droge
Format: Theses and Dissertations
Language:English
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10356/55737
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Institution: Nanyang Technological University
Language: English