Use of peptide asparginyl ligases (PALs) in generating alternative non-Ig protein-drug conjugates for cancer therapy

• المؤلف الرئيسي: See, Julia Jing Yi
• مؤلفون آخرون: Liu Chuan Fa
• التنسيق: Final Year Project
• اللغة: English
• منشور في: Nanyang Technological University 2023
• الموضوعات: Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/167167
• المؤسسة: Nanyang Technological University

Past research on antibody–drug conjugates (ADCs) focused on protein site-specific modification as chemical conjugation lacks site-selectivity. And despite monoclonal antibodies being the most common immunotherapeutic agent, its applicability & functionality are limited by several restrictions. T...