Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus

Progesterone receptor (PGR) is a master regulator of uterine function through antagonistic and synergistic interplays with oestrogen receptors. PGR action is primarily mediated by activation functions AF1 and AF2, but their physiological significance is unknown.

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Bibliographic Details
Main Authors: Lee, Shi Hao, Lim, Chew Leng, Shen, Wei, Tan, Samuel Ming Xuan, Woo, Amanda Rui En, Yap, Yeannie H. Y., Sian, Caitlyn Ang Su, Goh, Wilson Wen Bin, Yu, Wei-Ping, Li, Li, Lin, Valerie Chun Ling
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences
Endometrium
Activation Function 1
Online Access:https://hdl.handle.net/10356/168580
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/168580

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