Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains

• المؤلفون الرئيسيون: Yeo, Samuel Jianjie, Ying, Chen, Fullwood, Melissa Jane, Tergaonkar, Vinay
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Topologically Associating Domains; Noncoding RNAs
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/168913
• المؤسسة: Nanyang Technological University

Topologically associating domains (TADs) are integral to spatial genome organization, instructing gene expression, and cell fate. Recently, several advances have uncovered roles for noncoding RNAs (ncRNAs) in the regulation of the form and function of mammalian TADs. Phase separation has also emerge...