Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains

• Main Authors: Yeo, Samuel Jianjie, Ying, Chen, Fullwood, Melissa Jane, Tergaonkar, Vinay
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2023
• 主題: Science::Biological sciences; Topologically Associating Domains; Noncoding RNAs
• 在線閱讀: https://hdl.handle.net/10356/168913
• 機構: Nanyang Technological University

Topologically associating domains (TADs) are integral to spatial genome organization, instructing gene expression, and cell fate. Recently, several advances have uncovered roles for noncoding RNAs (ncRNAs) in the regulation of the form and function of mammalian TADs. Phase separation has also emerge...