Substrate architecture effect on siRNA silencing.

• Main Author: Koh, Hwee Ciah.
• Other Authors: Chew Sing Yian
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology
• Online Access: http://hdl.handle.net/10356/16897
• Institution: Nanyang Technological University

Electrospinning of polymeric materials has emerged as a versatile tool for constructing fibrous scaffolds with micro to nanoscale topology similar to the ECM. In this study, human embryonic kidney cells (HEK293) were cultured on electrospun poly (ε-caprolactone) (PCL) fibrous scaffolds. The average...