Persistent spectral simplicial complex-based machine learning for chromosomal structural analysis in cellular differentiation
The three-dimensional (3D) chromosomal structure plays an essential role in all DNA-templated processes, including gene transcription, DNA replication and other cellular processes. Although developing chromosome conformation capture (3C) methods, such as Hi-C, which can generate chromosomal contact...
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Main Authors: | Gong, Weikang, Wee, Junjie, Wu, Min-Chun, Sun, Xiaohan, Li, Chunhua, Xia, Kelin |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2023
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/168972 |
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Institution: | Nanyang Technological University |
Language: | English |
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