Persistent spectral simplicial complex-based machine learning for chromosomal structural analysis in cellular differentiation
The three-dimensional (3D) chromosomal structure plays an essential role in all DNA-templated processes, including gene transcription, DNA replication and other cellular processes. Although developing chromosome conformation capture (3C) methods, such as Hi-C, which can generate chromosomal contact...
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Main Authors: | , , , , , |
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格式: | Article |
語言: | English |
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2023
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在線閱讀: | https://hdl.handle.net/10356/168972 |
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