Persistent spectral simplicial complex-based machine learning for chromosomal structural analysis in cellular differentiation

The three-dimensional (3D) chromosomal structure plays an essential role in all DNA-templated processes, including gene transcription, DNA replication and other cellular processes. Although developing chromosome conformation capture (3C) methods, such as Hi-C, which can generate chromosomal contact...

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Main Authors: Gong, Weikang, Wee, Junjie, Wu, Min-Chun, Sun, Xiaohan, Li, Chunhua, Xia, Kelin
其他作者: School of Physical and Mathematical Sciences
格式: Article
語言:English
出版: 2023
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在線閱讀:https://hdl.handle.net/10356/168972
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