Cryo-EM structure of the Mycobacterium abscessus F1-ATPase

• المؤلفون الرئيسيون: Wong, Chui Fann, Leow, Chen Yen, Grüber, Gerhard
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences::Biochemistry; Science::Biological sciences::Biophysics; ATP Synthase; Bioenergetics; Electron Microscopy; Infectious Diseases; Mycobacterium; Non-Tuberculous Mycobacteria
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/169214

The cases of lung disease caused by non-tuberculous mycobacterium Mycobacterium abscessus (Mab) are increasing and not reliably curable. Repurposing of anti-tuberculosis inhibitors brought the oxidative phosphorylation pathway with its final product ATP, formed by the essential F1FO-ATP synthase (su...