Molecular recognition in protein-DNA assemblies

• Main Author: Davey, Curt Alexander
• Other Authors: School of Biological Sciences
• Format: Research Report
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Deoxyribonucleic acids
• Online Access: http://hdl.handle.net/10356/16926
• Institution: Nanyang Technological University

We initially completed our first project on designing and characterizing synthetic DNA-bending factors as tools for investigating and controlling gene regulation and DNA recombination. Engineered single chain proteins based on the bacterial integration host factor, scIHFs, hold promise for the desi...