Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort

Skin diseases impact significantly on the quality of life and psychology of patients. Obesity has been observed as a risk factor for skin diseases. Skin epidermal barrier dysfunctions are typical manifestations across several dermatological disturbances.

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Main Authors:	Yew, Yik Weng, Mina, Theresia, Ng, Hong Kiat, Lam, Benjamin Chih Chiang, Riboli, Elio, Lee, Eng Sing, Lee, Jimmy, Ngeow, Joanne, Elliott, Paul, Thng, Steven Tien Guan, Chambers, John Campbell, Loh, Marie
Other Authors:	Lee Kong Chian School of Medicine (LKCMedicine)
Format:	Article
Language:	English
Published:	2023
Subjects:	Science::Medicine Skin Barrier Obesity Mendelian Randomization
Online Access:	https://hdl.handle.net/10356/169564
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-1695642023-07-30T15:38:01Z Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort Yew, Yik Weng Mina, Theresia Ng, Hong Kiat Lam, Benjamin Chih Chiang Riboli, Elio Lee, Eng Sing Lee, Jimmy Ngeow, Joanne Elliott, Paul Thng, Steven Tien Guan Chambers, John Campbell Loh, Marie Lee Kong Chian School of Medicine (LKCMedicine) National Skin Centre Khoo Teck Puat Hospital National Healthcare Group Polyclinic Institute of Mental Health National Cancer Centre Genome Institute of Singapore, A*STAR Science::Medicine Skin Barrier Obesity Mendelian Randomization Skin diseases impact significantly on the quality of life and psychology of patients. Obesity has been observed as a risk factor for skin diseases. Skin epidermal barrier dysfunctions are typical manifestations across several dermatological disturbances. Ministry of Health (MOH) National Medical Research Council (NMRC) Published version This work was supported by the Singapore Ministry of Health’s National Medical Research Council under its OF-LCG funding scheme (NMRC Project Ref. MOH-000271-00) and intramural funding from Nanyang Technological University, Lee Kong Chian School of Medicine and the National Healthcare Group. Dr. Yik Weng Yew is supported by the Singapore Ministry of Health’s National Medical Research Council under its Transition Award funding scheme (NMRC Project Ref. NMRC/ MOH-TA19nov-0004). Professor John Chambers is supported by the Singapore Ministry of Health’s National Medical Research Council under its STaR funding scheme (NMRC Project Ref. NMRC/STaR/0028/2017). 2023-07-24T08:18:29Z 2023-07-24T08:18:29Z 2023 Journal Article Yew, Y. W., Mina, T., Ng, H. K., Lam, B. C. C., Riboli, E., Lee, E. S., Lee, J., Ngeow, J., Elliott, P., Thng, S. T. G., Chambers, J. C. & Loh, M. (2023). Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort. International Journal of Obesity. https://dx.doi.org/10.1038/s41366-023-01343-z 0307-0565 https://hdl.handle.net/10356/169564 10.1038/s41366-023-01343-z 37479793 en MOH-000271-00 NMRC/ MOH-TA19nov-0004 NMRC/STaR/0028/2017 International Journal of Obesity © 2023 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. application/pdf application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Science::Medicine Skin Barrier Obesity Mendelian Randomization
spellingShingle	Science::Medicine Skin Barrier Obesity Mendelian Randomization Yew, Yik Weng Mina, Theresia Ng, Hong Kiat Lam, Benjamin Chih Chiang Riboli, Elio Lee, Eng Sing Lee, Jimmy Ngeow, Joanne Elliott, Paul Thng, Steven Tien Guan Chambers, John Campbell Loh, Marie Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort
description	Skin diseases impact significantly on the quality of life and psychology of patients. Obesity has been observed as a risk factor for skin diseases. Skin epidermal barrier dysfunctions are typical manifestations across several dermatological disturbances.
author2	Lee Kong Chian School of Medicine (LKCMedicine)
author_facet	Lee Kong Chian School of Medicine (LKCMedicine) Yew, Yik Weng Mina, Theresia Ng, Hong Kiat Lam, Benjamin Chih Chiang Riboli, Elio Lee, Eng Sing Lee, Jimmy Ngeow, Joanne Elliott, Paul Thng, Steven Tien Guan Chambers, John Campbell Loh, Marie
format	Article
author	Yew, Yik Weng Mina, Theresia Ng, Hong Kiat Lam, Benjamin Chih Chiang Riboli, Elio Lee, Eng Sing Lee, Jimmy Ngeow, Joanne Elliott, Paul Thng, Steven Tien Guan Chambers, John Campbell Loh, Marie
author_sort	Yew, Yik Weng
title	Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort
title_short	Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort
title_full	Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort
title_fullStr	Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort
title_full_unstemmed	Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort
title_sort	investigating causal relationships between obesity and skin barrier function in a multi-ethnic asian general population cohort
publishDate	2023
url	https://hdl.handle.net/10356/169564
_version_	1773551345309057024

Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort

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