Beyond the TPP+ "gold standard": a new generation mitochondrial delivery vector based on extended PN frameworks

Mitochondrial targeting represents an attractive strategy for treating metabolic, degenerative and hyperproliferative diseases, since this organelle plays key roles in essential cellular functions. Triphenylphosphonium (TPP+) moieties - the current "gold standard" - have been widely used a...

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Bibliographic Details
Main Authors: Ong, How Chee, Coimbra, João T. S., Ramos, Maria J., Xing, Bengang, Fernandes, Pedro A., García, Felipe
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10356/169778
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Institution: Nanyang Technological University
Language: English