Molecular functions of the nuclear lamina in premature cell ageing

Hutchinson-Gilford Progeria Syndrome (HGPS) is a premature ageing syndrome that manifests as early as 1 year of age. Patients exhibit severe phenotypes such as bone defects, cardiovascular complications, and a mean lifespan of 14 years. HGPS is caused by a silent heterozygous mutation that results i...

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書目詳細資料
主要作者: Foo, Mattheus Xing Rong
其他作者: Peter Droge
格式: Thesis-Doctor of Philosophy
語言:English
出版: Nanyang Technological University 2023
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在線閱讀:https://hdl.handle.net/10356/169879
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