Structural and dynamical investigation of histone H2B in well-hydrated nucleosome core particles by solid-state NMR

• المؤلفون الرئيسيون: Shi, Xiangyan, Kannaian, Bhuvaneswari, Prasanna, Chinmayi, Soman, Aghil, Nordenskiöld, Lars
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Histone; Nucleosome
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/170947
• المؤسسة: Nanyang Technological University

H2A-H2B dimer is a key component of nucleosomes and an important player in chromatin biology. Here, we characterized the structure and dynamics of H2B in precipitated nucleosome core particles (NCPs) with a physiologically relevant concentration using solid-state NMR. Our recent investigation of H3-...