Trajectory of immune evasion and cancer progression in hepatocellular carcinoma

• المؤلفون الرئيسيون: Nguyen, Phuong H. D., Wasser, Martin, Tan, Chong Teik, Lim, Chun Jye, Lai, Hannah L. H., Seow, Justine Jia Wen, DasGupta, Ramanuj, Phua, Cheryl Z. J., Ma, Siming, Yang, Jicheng, Sheena D/O Suthen, Tam, Wai Leong, Lim, Tony K. H., Yeong, Joe, Leow, Wei Qiang, Pang, Yin Huei, Soon, Gwyneth, Loh, Tracy Jiezhen, Wan, Wei Keat, Chan, Chung Yip, Cheow, Peng Chung, Toh, Han Chong, Kow, Alfred, Dan, Yock Young, Kam, Juinn Huar, Iyer, Shridhar, Madhavan, Krishnakumar, Chung, Alexander, Bonney, Glenn K., Goh, Brian K. P., Fu, Naiyang, Yu, Victor C., Zhai, Weiwei, Albani, Salvatore, Chow, Pierce K. H., Chew, Valerie
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Cancer Immunotherapy; Transcriptome
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/171173
• المؤسسة: Nanyang Technological University

Immune evasion is key to cancer initiation and later at metastasis, but its dynamics at intermediate stages, where potential therapeutic interventions could be applied, is undefined. Here we show, using multi-dimensional analyses of resected tumours, their adjacent non-tumour tissues and peripheral...