Achieving molecular recognition of structural analogues in surface-enhanced Raman spectroscopy: inducing charge and geometry complementarity to mimic molecular docking

• Main Authors: Leong, Shi Xuan, Kao, Ya-Chuan, Han, Xuemei, Poh, Zhong Wei, Chen, Jaslyn Ru Ting, Tan, Emily Xi, Leong, Yong Xiang, Lee, Yih Hong, Teo, Wei Xuan, Yip, George W., Lam, Yulin, Ling, Xing Yi
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Chemical engineering; Isomers; Molecular Probes
• Online Access: https://hdl.handle.net/10356/171344
• Institution: Nanyang Technological University

Molecular recognition of complex isomeric biomolecules remains challenging in surface-enhanced Raman scattering (SERS) spectroscopy due to their small Raman cross-sections and/or poor surface affinities. To date, the use of molecular probes has achieved excellent molecular sensitivities but still su...