Evaluation of NG-Test CARBA 5 version 2, Cepheid Xpert Carba-R, and carbapenem inactivation methods in comparison to whole-genome sequencing for the identification of carbapenemases in non-fermenting Gram-negative bacilli

• Main Authors: Khoo, Bo Yan, Hon, Pei Yun, Leong, Janice, Sridatta, Prakki Sai Rama, Thevasagayam, Natascha May, Loy, Dennis Song Qi, Chua, Jasmine J. Y., Ang, Brenda Sze Peng, Chow, Angela, Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Vasoo, Shawn
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; NG-Test CARBA 5; Xpert Carba-R
• Online Access: https://hdl.handle.net/10356/171589
• Institution: Nanyang Technological University

NG-Test CARBA 5 (NG-Biotech) is a rapid in vitro multiplex immunoassay for the phenotypic detection and differentiation of the "big five" carbapenemase families (KPC, OXA-48-like, VIM, IMP, and NDM). Version 2 of this assay was evaluated alongside the Xpert Carba-R assay (Cepheid, Inc.), t...