AcrPred: a hybrid optimization with enumerated machine learning algorithm to predict anti-CRISPR proteins

• Main Authors: Dao, Fu-Ying, Liu, Meng-Lu, Su, Wei, Lv, Hao, Zhang, Zhao-Yue, Lin, Hao, Liu, Li
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Anti-CRISPR Protein; Machine Learning
• Online Access: https://hdl.handle.net/10356/172143
• Institution: Nanyang Technological University

CRISPR-Cas, as a tool for gene editing, has received extensive attention in recent years. Anti-CRISPR (Acr) proteins can inactivate the CRISPR-Cas defense system during interference phase, and can be used as a potential tool for the regulation of gene editing. In-depth study of Anti-CRISPR proteins...