Upregulated blood miR-150-5p in alzheimer's disease dementia is associated with cognition, cerebrospinal fluid amyloid-β, and cerebral atrophy

• Main Authors: Chia, Sook Yoong, Vipin, Ashwati, Ng, Kok Pin, Tu, Haitao, Bommakanti, Ananth, Wang, Brian Zhiyang, Tan, Jayne Yi, Zailan, Fatin Zahra, Ng, Adeline Su Lyn, Ling, Shuo-Chien, Okamura, Katsutomo, Tan, Eng-King, Kandiah, Nagaendran, Zeng, Li
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Alzheimer’s Dementia; Biomarker
• Online Access: https://hdl.handle.net/10356/172176
• Institution: Nanyang Technological University

There is an urgent need for noninvasive, cost-effective biomarkers for Alzheimer's disease (AD), such as blood-based biomarkers. They will not only support the clinical diagnosis of dementia but also allow for timely pharmacological and nonpharmacological interventions and evaluations.