Allosteric inhibition of the T cell receptor by a designed membrane ligand
The T cell receptor (TCR) is a complex molecular machine that directs the activation of T cells, allowing the immune system to fight pathogens and cancer cells. Despite decades of investigation, the molecular mechanism of TCR activation is still controversial. One of the leading activation hypothese...
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Main Authors: | Ye, Yujie, Morita, Shumpei, Chang, Justin J., Buckley, Patrick M., Wilhelm, Kiera B., DiMaio, Daniel, Groves, Jay T., Barrera, Francisco N. |
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Other Authors: | Institute for Digital Molecular Analytics and Science (IDMxS) |
Format: | Article |
Language: | English |
Published: |
2024
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/173766 |
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Institution: | Nanyang Technological University |
Language: | English |
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