Structural and biochemical characterization of NS2BCF48-NS3fl from flaviviruses

• المؤلف الرئيسي: Teo, Fyn Chwee Fang
• مؤلفون آخرون: Luo Dahai
• التنسيق: Final Year Project
• اللغة: English
• منشور في: Nanyang Technological University 2024
• الموضوعات: Medicine, Health and Life Sciences; Flaviviruses; Dengue virus; NS2B-NS3; Protease assay; Crosslinking mass spectrometry
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/175412
• المؤسسة: Nanyang Technological University

Dengue virus (DENV) is an emerging and re-emerging mosquito-borne virus of significant public health concern. The DENV has a single-stranded RNA genome that is translated into a polyprotein and then cleaved into individual viral proteins by the host and viral proteases. Non-structural (NS) protein-3...