Analysis of alternative splicing profiles and the role of RBM47 in myeloid maturation

Myeloid leukocytes, such as neutrophils and monocytes, are critical for innate immunity. As splicing defects are common in malignancies that disrupt myeloid maturation, we hypothesise that alternative splicing (AS) programmes are important in regulating myelopoiesis. To study AS during human neu...

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Bibliographic Details
Main Author: Sim, Donald Yuhui
Other Authors: Francesc Xavier Roca Castella
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/175904
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Institution: Nanyang Technological University
Language: English