Synergistic copper-aminocatalysis for direct tertiary -alkylation of ketones with electron-deficient alkanes

• المؤلفون الرئيسيون: Shan, Qi-Chao, Wu, You-Wei, Chen, Mu-Xiang, Zhao, Xuefei, Loh, Teck-Peng, Hu, Xu-Hong
• مؤلفون آخرون: School of Chemistry, Chemical Engineering and Biotechnology
• التنسيق: مقال
• اللغة: English
• منشور في: 2024
• الموضوعات: Chemistry; Ketones; Tertiary alkylation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/178845

In this study, a novel approach for the tertiary α-alkylation of ketones using alkanes with electron-deficient C─H bonds is presented, employing a synergistic catalytic system combining inexpensive copper salts with aminocatalysis. This methodology addresses the limitations of traditional alkylation...