Synergistic copper-aminocatalysis for direct tertiary -alkylation of ketones with electron-deficient alkanes
In this study, a novel approach for the tertiary α-alkylation of ketones using alkanes with electron-deficient C─H bonds is presented, employing a synergistic catalytic system combining inexpensive copper salts with aminocatalysis. This methodology addresses the limitations of traditional alkylation...
Saved in:
Main Authors: | Shan, Qi-Chao, Wu, You-Wei, Chen, Mu-Xiang, Zhao, Xuefei, Loh, Teck-Peng, Hu, Xu-Hong |
---|---|
Other Authors: | School of Chemistry, Chemical Engineering and Biotechnology |
Format: | Article |
Language: | English |
Published: |
2024
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/178845 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Carbene-catalyzed desymmetrization of 1,3-diols: access to optically enriched tertiary alkyl chlorides
by: Li, Bao-Sheng, et al.
Published: (2017) -
Palladium-catalyzed para-selective alkylation of electron-deficient arenes
by: Jiao, Zhiwei, et al.
Published: (2019) -
Palladium-Catalyzed Arylation of Ketones and Acetonitrile with Ortho Alkylation of Aryl Rings: De Novo Synthesis of Tetralines and Benzocycloheptenes
by: Lei, Chuanhu, et al.
Published: (2017) -
Chromium(III)-catalyzed addition of water and alcohol to α,β-unsaturated ketones for the synthesis of β-hydroxyl and β-alkoxyl ketones in aqueous media
by: Yun, Jin-Jin, et al.
Published: (2020) -
Ytterbium-catalyzed hydroboration of aldehydes and ketones
by: Wang, Weifan, et al.
Published: (2020)