An enzymatic oxidation cascade converts δ-thiolactone anthracene to anthraquinone in the biosynthesis of anthraquinone-fused enediynes
Anthraquinone-fused enediynes are anticancer natural products featuring a DNA-intercalating anthraquinone moiety. Despite recent insights into anthraquinone-fused enediyne (AQE) biosynthesis, the enzymatic steps involved in anthraquinone biogenesis remain to be elucidated. Through a combination of i...
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| Main Authors: | , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/180505 |
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| Institution: | Nanyang Technological University |
| Language: | English |