Tumor redox-responsive minimalist B/Fe nano-chains for chemodynamically enhanced ferroptosis and synergistic boron neutron capture therapy

• Main Authors: Wang, Mixue, Hao, Haotian, Bai, Peirong, Wu, Jiayan, Zhang, Zizhu, Liu, Tong, Yang, Yongzhen, Li, Liping, Pu, Kanyi, Zhang, Ruiping
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Chemistry; Boron neutron capture therapy; Size-tunable behavior
• Online Access: https://hdl.handle.net/10356/180697
• Institution: Nanyang Technological University

Boron neutron capture therapy (BNCT) as a binary targeted particle radiotherapy strategy has shown potent anti-cancer potential. However, biological barriers and restricted blood supply pose challenges in achieving adequate boron concentration within deep-seated tumor lesions. BNCT with other anti-c...