Development of sequencing methods to illuminate the epitranscriptome

• المؤلف الرئيسي: Heng, Joel Jia Wei
• مؤلفون آخرون: Tan Meng How
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2025
• الموضوعات: Medicine, Health and Life Sciences; RNA; Modifications; Sequencing; Editing; Methylation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/182139

RNA modifications are chemical marks which expand genetic vocabulary beyond the canonical A, G, C, and T/U. The first RNA modification was discovered in 1957. While over 160 varieties of RNA modifications have been recorded since, the discovery that certain RNA modifications are reversible and can b...