The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

Solar UVB light causes damage to the outermost layer of skin. This insult induces rapid local responses, such as dermal inflammation, keratinocyte cell death, and epidermal thickening, all of which have traditionally been associated with DNA damage response signaling. Another stress response that is...

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Bibliographic Details
Main Authors: Vind, Anna Constance, Wu, Zhenzhen, Muhammad Jasrie Firdaus, Snieckute, Goda, Toh, Gee Ann, Jessen, Malin, Martínez, José Francisco, Haahr, Peter, Andersen, Thomas Levin, Blasius, Melanie, Koh, Li Fang, Maartensson, Nina Loeth, Common, John E. A., Gyrd-Hansen, Mads, Zhong, Franklin, Bekker-Jensen, Simon
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2025
Subjects:
Medicine, Health and Life Sciences
Pyroptosis
Ribotoxic stress response
Online Access:https://hdl.handle.net/10356/182270
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/182270

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