On-chip NADH detection in multicellular models using an AlGaN/GaN photodetector array with enhanced sensitivity

• Main Authors: Xiong, Zhongshu, Fang, Guocheng, Mondal, Ramit Kumar, Liao, Yikai, Nie, Ningyuan, Chen, Yu-Cheng, Kim, Munho
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2025
• Subjects: Engineering; 3D multicellular models; Biosensor
• Online Access: https://hdl.handle.net/10356/182785
• Institution: Nanyang Technological University

Nicotinamide adenine dinucleotide (NAD) is a pivotal coenzyme, existing in its oxidized form (NAD+) and reduced form (NADH). Both are essential in cellular redox reactions and are implicated in energy production and cancer. Current NADH detection methods often involve complex optical measurements. W...