Biochemical and structural studies on the molecular interaction between P53 transcriptional activation domain and anti-apoptotic protein BCL-XL

This is due to its critical role in the regulation of apoptosis and control of cancer formation. p53 is believed to be the most important tumor suppressor protein and abnormality of p53 causes cancers and many other diseases. Functional studies revealed that p53 is an important transcriptional acti...

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Bibliographic Details
Main Author: Xu, Huibin
Other Authors: Yoon, Ho Sup
Format: Theses and Dissertations
Language:English
Published: 2009
Subjects:
Online Access:https://hdl.handle.net/10356/18852
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Institution: Nanyang Technological University
Language: English