Functional characterization of human respiratory syncytial virus (hRSV) small hydrophobic protein (SH) through small interfering RNA (siRNA) that targets SH.

• Main Author: Ngan, Grace Jie Yin.
• Other Authors: Richard J. Sugrue
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/19055
• Institution: Nanyang Technological University

Small hydrophobic (SH) protein is a transmembrane protein from Human Respiratory Syncytial Virus (hRSV). Though its gene sequence is highly conserved in clinical isolates, the function remains debatable in viral pathogenesis and replication. In this study, small interfering RNA (siRNA) targeting SH...