Fabrication and characterization of barium strontium titanate film based biosensor
In this project, biosensors based on a sol-gel derived Barium Strontium Titanate (BST) composite film are studied. Poly(TMS-r-NHS) [TMS: 3-(trimethoxysilyl)propyl methacrylate; NHS: N-hydroxysuccinimide] is used to modify the BST surface for protein immobilization. Two types of biosensors were devel...
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| Other Authors: | |
| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/20679 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | In this project, biosensors based on a sol-gel derived Barium Strontium Titanate (BST)
composite film are studied. Poly(TMS-r-NHS) [TMS: 3-(trimethoxysilyl)propyl
methacrylate; NHS: N-hydroxysuccinimide] is used to modify the BST surface for
protein immobilization. Two types of biosensors were developed and investigated.
First, Bovine Serum Albumin (BSA) was immobilized on the poly(TMS-r-NHS)
followed by anti-BSA. On the second type of biosensors, cloned Epstein-Barr virus
(EBV) was imlTIobilized on the poly(TMS-r-NHS) followed by anti-EBV. Significant
impedance increlnents were observed on both biosensors. These impedance
increments were attributed to three factors. |
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