Copper-catalysed β-silylation of α,β-unsaturated esters under mild reaction conditions.

• Main Author: Siti Suhaila Sulaiman.
• Other Authors: Loh Teck Peng
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
• Online Access: http://hdl.handle.net/10356/38631
• Institution: Nanyang Technological University

A highly-efficient β-silylation of α, β-unsaturated esters was developed, utilizing N-heterocyclic carbene copper(I) catalyst via a unique protocol based on Si ̶B activation. By employing MeOH as a basic additive which is necessary to promote the reaction, the β-silylation products can be readily ob...