Copper-catalysed β-silylation of α,β-unsaturated esters under mild reaction conditions.

• 主要作者: Siti Suhaila Sulaiman.
• 其他作者: Loh Teck Peng
• 格式: Final Year Project
• 語言: English
• 出版: 2010
• 主題: DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
• 在線閱讀: http://hdl.handle.net/10356/38631
• 機構: Nanyang Technological University

A highly-efficient β-silylation of α, β-unsaturated esters was developed, utilizing N-heterocyclic carbene copper(I) catalyst via a unique protocol based on Si ̶B activation. By employing MeOH as a basic additive which is necessary to promote the reaction, the β-silylation products can be readily ob...