Stability of peptide nucleic acid influenced by peptoid-like sidechains : MD simulation study.

• المؤلف الرئيسي: Yeo, Sven Hwea Jie.
• مؤلفون آخرون: Mu Yuguang
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2010
• الموضوعات: DRNTU::Science::Biological sciences::Biochemistry
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/38930
• المؤسسة: Nanyang Technological University

Peptide nucleic acid (PNA) is one of the most promising candidates for next-generation antisense technology. Other than high specificity and ability to be engineered to target, it offers enhanced stability, fidelity and strand invasion capabilities. Rapid developments in this field include synthesis...