Application of COLD-PCR for improved detection of EGFR mutations in clinical samples.

Due to the significance of mutation status of the epidermal growth factor receptor (EGFR) gene in non-small-cell lung cancer (NSCLC) affecting patient response to tyrosine kinase inhibitors (TKI), the more sensitive and robust the method used to detect the mutations, the better. It has been suggeste...

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Bibliographic Details
Main Author: Zhang, Zhi Xuan.
Other Authors: School of Biological Sciences
Format: Final Year Project
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10356/41758
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Institution: Nanyang Technological University
Language: English