Application of COLD-PCR for improved detection of EGFR mutations in clinical samples.
Due to the significance of mutation status of the epidermal growth factor receptor (EGFR) gene in non-small-cell lung cancer (NSCLC) affecting patient response to tyrosine kinase inhibitors (TKI), the more sensitive and robust the method used to detect the mutations, the better. It has been suggeste...
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Format: | Final Year Project |
Language: | English |
Published: |
2010
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Online Access: | http://hdl.handle.net/10356/41758 |
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Institution: | Nanyang Technological University |
Language: | English |