Pharmacogenetics of VKORC1 in warfarin resistant patients.

Warfarin is a commonly prescribed anticoagulant that displays wide inter-individual variability in treatment response and dosage. It acts by inhibiting the vitamin K epoxide reductase (VKOR) enzyme in the liver. Genetic variations in vitamin K epoxide reductase complex subunit 1(VKORC1), have been a...

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Bibliographic Details
Main Author: Ong, Jacqueline Kai Mei.
Other Authors: Balram Chowbay
Format: Final Year Project
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10356/41759
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Institution: Nanyang Technological University
Language: English