Molecular interaction of tumor suppressor protein p53 and anti-apoptotic proteins Bcl-2 and Bcl-XL.

• Main Author: Yoon, Ho Sup.
• Other Authors: School of Biological Sciences
• Format: Research Report
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/41823
• Institution: Nanyang Technological University

Emerging evidences suggest that transcription-independent mechanism of p53 appears to make an important contribution to the overall p53-dependent apoptosis. The molecular interaction between Bel-XL and p53 is critical for this regulation. To understand the nature of the molecular recognition between...