An in silico, in vitro and in vivo study of the structural and functional features of SARS small protein E and its contribution to viral morphogenesis and apoptosis.

• Main Author: Torres, Jaume.
• Other Authors: School of Biological Sciences
• Format: Research Report
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/41873
• Institution: Nanyang Technological University

Severe acute respiratory syndrome (SARS) is a respiratory disease in humans caused by the SARS coronavirus (SCoV). All coronaviruses encode a small hydrophobic envelope (E) protein, which mediates viral assembly and morphogenesis by an unknown mechanism. When E proteins are synthesized alone, the...