Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters

Triple Negative Breast cancer (TNBC) is a newly studied subtype of breast cancer. Existing literature demonstrates that as cancer advances, the tumor cells will undergo epithelial-mesenchymal transition (EMT) to form secondary tumors at distant site. E-cadherin and Vimentin are biomarkers for epithe...

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Main Author:	Chai, Xiu Hui
Other Authors:	School of Biological Sciences
Format:	Final Year Project
Language:	English
Published:	2011
Subjects:	DRNTU::Science::Medicine::Biosensors
Online Access:	http://hdl.handle.net/10356/45029
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-450292023-02-28T18:00:50Z Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters Chai, Xiu Hui School of Biological Sciences Jabed Iqbal DRNTU::Science::Medicine::Biosensors Triple Negative Breast cancer (TNBC) is a newly studied subtype of breast cancer. Existing literature demonstrates that as cancer advances, the tumor cells will undergo epithelial-mesenchymal transition (EMT) to form secondary tumors at distant site. E-cadherin and Vimentin are biomarkers for epithelial and mesenchymal states respectively. β-catenin is involved in maintaining stable epithelial complex with E-cadherin and in signalling pathway implicated in tumorogenesis. Bachelor of Science in Biological Sciences 2011-06-08T06:29:34Z 2011-06-08T06:29:34Z 2011 2011 Final Year Project (FYP) http://hdl.handle.net/10356/45029 en Nanyang Technological University 38 p. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	DRNTU::Science::Medicine::Biosensors
spellingShingle	DRNTU::Science::Medicine::Biosensors Chai, Xiu Hui Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
description	Triple Negative Breast cancer (TNBC) is a newly studied subtype of breast cancer. Existing literature demonstrates that as cancer advances, the tumor cells will undergo epithelial-mesenchymal transition (EMT) to form secondary tumors at distant site. E-cadherin and Vimentin are biomarkers for epithelial and mesenchymal states respectively. β-catenin is involved in maintaining stable epithelial complex with E-cadherin and in signalling pathway implicated in tumorogenesis.
author2	School of Biological Sciences
author_facet	School of Biological Sciences Chai, Xiu Hui
format	Final Year Project
author	Chai, Xiu Hui
author_sort	Chai, Xiu Hui
title	Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
title_short	Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
title_full	Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
title_fullStr	Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
title_full_unstemmed	Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
title_sort	study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
publishDate	2011
url	http://hdl.handle.net/10356/45029
_version_	1759854066379259904

Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters

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