Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters

• Main Author: Chai, Xiu Hui
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Medicine::Biosensors
• Online Access: http://hdl.handle.net/10356/45029
• Institution: Nanyang Technological University

Triple Negative Breast cancer (TNBC) is a newly studied subtype of breast cancer. Existing literature demonstrates that as cancer advances, the tumor cells will undergo epithelial-mesenchymal transition (EMT) to form secondary tumors at distant site. E-cadherin and Vimentin are biomarkers for epithe...