Pharmacogenetics of the prostaglandin-endoperoxide synthase 2 (PTGS-2) 5' and 3' untranslated regions in three distinct Asian populations.

Cyclooxygenase-2 (COX-2) is an enzyme induced in response to mitogens, tumour promoters, and cytokines. Gene expression of COX-2 is found to be upregulated in solid tumours. Polymorphisms in regulatory regions of PTGS-2 encoding COX-2 were demonstrated to influence COX-2 expression levels and alter...

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Bibliographic Details
Main Author: Yip, Fong Ee.
Other Authors: Kristen Elizabeth Sadler
Format: Final Year Project
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10356/45272
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Institution: Nanyang Technological University
Language: English