Pharmacogenetics of the prostaglandin-endoperoxide synthase 2 (PTGS-2) 5' and 3' untranslated regions in three distinct Asian populations.
Cyclooxygenase-2 (COX-2) is an enzyme induced in response to mitogens, tumour promoters, and cytokines. Gene expression of COX-2 is found to be upregulated in solid tumours. Polymorphisms in regulatory regions of PTGS-2 encoding COX-2 were demonstrated to influence COX-2 expression levels and alter...
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| 格式: | Final Year Project |
| 語言: | English |
| 出版: |
2011
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| 在線閱讀: | http://hdl.handle.net/10356/45272 |
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