Using single-molecule techniques to study DNA mechanics and DNA-protein interactions

This work focuses on two single-molecule techniques: Magnetic Tweezers and Tethered Particle Motion (TPM). Magnetic Tweezers were used to study the DNA overstretching transition from the B-form to the S-form at 65 pN. The operations of the magnetic tweezers were studied and the resolution of its mea...

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Bibliographic Details
Main Author: Fang, Keyi
Other Authors: Phan Anh Tuan
Format: Final Year Project
Language:English
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10356/49068
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Institution: Nanyang Technological University
Language: English