Role of cargo receptors in Synphilin-1 mediated selective autophagy of protein aggregates.
The ANK-1 domain of synphilin-1 has been recently identified to able to impart autophagic clearance signals to certain disease-linked protein inclusions that were previously resistant to clearance by autophagy. To examine whether ANK1 cooperates with known cargo adaptors, p62 and NBR1, in mediating...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2012
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| Online Access: | http://hdl.handle.net/10356/49281 |
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| Institution: | Nanyang Technological University |
| Language: | English |