Molecular mechanisms underlying selective clearance of protein aggregates and mitochondria by autophagy

Autophagy is an important quality control mechanism that degrades unwanted or damaged cellular components in the lysosomes to maintain cellular homeostasis. Autophagy was once thought as a non-selective catabolic process. However, it is now recognize that the cells can upregulate selective forms of...

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Bibliographic Details
Main Author: Tan, Sijie
Other Authors: Wong Siew Peng Esther
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/72655
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Institution: Nanyang Technological University
Language: English