Molecular mechanisms underlying selective clearance of protein aggregates and mitochondria by autophagy

• Main Author: Tan, Sijie
• Other Authors: Wong Siew Peng Esther
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences::Cytology
• Online Access: http://hdl.handle.net/10356/72655
• Institution: Nanyang Technological University

Autophagy is an important quality control mechanism that degrades unwanted or damaged cellular components in the lysosomes to maintain cellular homeostasis. Autophagy was once thought as a non-selective catabolic process. However, it is now recognize that the cells can upregulate selective forms of...