New DNA motifs : structure and potential activity against HIV and cancer

• Main Author: Do, Ngoc Quang
• Other Authors: Phan Anh Tuan
• Format: Theses and Dissertations
• Language: English
• Published: 2012
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/50612
• Institution: Nanyang Technological University

Guanine-rich oligonucleotides have the ability to adopt non-canonical structures, called G-quadruplexes. G-quadruplex structures are highly polymorphic, depending on their sequences and environmental conditions. In this thesis, we study structural features of G-quadruplexes adopted by oligonucleotid...